How Long Does Ketamine Work for Depression?

Reviewed by: Michelle Dees, MD
Does ketamine work for depression?
Table of Contents
    Add a header to begin generating the table of contents

    Ketamine has emerged as a promising treatment for depression, especially for individuals who have not responded to traditional antidepressants. The duration of its effectiveness can vary from person to person, but generally, the antidepressant effects of ketamine can last from a few days to several weeks after a single infusion. Most patients experience a rapid relief of depressive symptoms within hours to days following the treatment, which is significantly faster than conventional antidepressants that may take weeks to show effects.

    In clinical practice, the maintenance of ketamine’s antidepressant effects often requires repeated administrations. A typical protocol might involve an initial series of infusions administered over a couple of weeks, followed by maintenance treatments at intervals ranging from once a week to once a month, depending on the individual’s response and needs. Research and clinical experience are continually refining these protocols to maximize the benefits and minimize potential side effects, ensuring that patients receive the most effective and sustainable relief from depression through ketamine therapy.


    Ketamine Treatment vs. Therapy

    Ketamine treatment and traditional therapy offer distinct approaches to managing depression, each with its own advantages. Ketamine treatment, often administered via intravenous infusion, nasal spray, or oral medication, provides rapid relief from depressive symptoms, often within hours or days. This is particularly beneficial for individuals experiencing severe or treatment-resistant depression, as it can offer a quick reprieve from debilitating symptoms and improve overall functioning in a short period. Additionally, ketamine’s unique mechanism of action, targeting the glutamate system, differentiates it from conventional antidepressants and provides an alternative for those who have not found relief with other medications.

    On the other hand, therapy, such as cognitive-behavioral therapy (CBT) or psychodynamic therapy, offers a longer-term solution by addressing the underlying causes and patterns of depression. Therapy involves regular sessions with a trained mental health professional, focusing on developing coping strategies, changing negative thought patterns, and improving emotional regulation. While the effects of therapy may take longer to manifest compared to ketamine treatment, the benefits are often more sustainable and can lead to lasting changes in a person’s mental health and overall well-being. Combining ketamine treatment with therapy can be particularly effective, offering immediate symptom relief while working towards long-term mental health improvements.

    Ready to Book An Appointment With Our Psychiatrists?

    How Long Does Ketamine Work for Depression?
    How Long Does Ketamine Work for Depression?
    How Long Does Ketamine Work for Depression?
    How Long Does Ketamine Work for Depression?
    How Long Does Ketamine Work for Depression?
    How Long Does Ketamine Work for Depression?
    How Long Does Ketamine Work for Depression?

    How Long Does a Patient Recieve Ketamine Therapy?

    The duration of ketamine therapy varies based on individual needs and treatment responses. Typically, the initial phase of treatment involves a series of infusions or administrations over a period of two to four weeks. During this phase, patients might receive ketamine two to three times a week, depending on their response to the treatment and the severity of their depression.

    After the initial phase, the frequency of ketamine treatments is often reduced as part of a maintenance phase. During maintenance, patients might receive ketamine once a week, biweekly, or even monthly. The exact schedule is tailored to the individual’s response and needs, with some patients requiring more frequent treatments to sustain the antidepressant effects, while others may maintain their benefits with less frequent dosing. Regular follow-ups with the treating psychiatrist are essential to monitor progress, adjust dosing schedules, and ensure the treatment’s continued effectiveness and safety.


    Do You Move On from Ketamine Therapy?

    Moving on from ketamine therapy depends on the individual’s progress and overall treatment plan. For some patients, ketamine therapy serves as a bridge to more long-term treatments, helping to alleviate severe symptoms quickly so they can engage more effectively in traditional therapies such as cognitive-behavioral therapy (CBT) or medication management. Once their depression is more manageable, these patients might gradually taper off ketamine under the guidance of their healthcare provider, transitioning to other forms of maintenance treatment.

    Other patients may find that periodic ketamine treatments remain a necessary part of their ongoing mental health regimen. For these individuals, ketamine therapy can continue to provide significant relief from depressive symptoms and help maintain their quality of life. It’s important to note that any decision to move on from ketamine therapy should be made collaboratively with a healthcare provider, taking into account the patient’s unique circumstances, treatment response, and overall mental health goals. Regular assessments and open communication with the treatment team are essential to determine the best course of action for each individual.


    Advantages of Ketamine Therapy at Our Clinic

    At Luxury Psychiatry Clinic, we offer a comprehensive and patient-centered approach to ketamine therapy, ensuring that each individual receives the highest standard of care tailored to their specific needs. One of the key advantages of receiving ketamine therapy at our clinic is our team of experienced and compassionate professionals who specialize in cutting-edge mental health treatments. Our staff includes board-certified psychiatrists, psychologists, and nurses who are dedicated to providing safe, effective, and personalized care.

    Another significant advantage of our clinic is the state-of-the-art facilities designed to create a comfortable and supportive environment for our patients. We prioritize patient comfort and privacy, ensuring that each treatment session is conducted in a serene and relaxing setting. Our clinic also integrates ketamine therapy with comprehensive mental health services, including psychotherapy and medication management, to provide a holistic approach to treatment. By offering a full spectrum of mental health care, we aim to enhance the effectiveness of ketamine therapy and support our patients in achieving long-term mental wellness.


    Start Ketamine Therapy Today

    If you or a loved one is struggling with depression and traditional treatments have not provided the relief you need, ketamine therapy might be the solution you’ve been searching for. At Luxury Psychiatry Clinic, our dedicated team is here to help you explore this innovative treatment option and determine if it’s right for you. Don’t let depression control your life any longer—take the first step towards a brighter future.

    Schedule an initial consultation appointment with us today to discuss your symptoms, treatment history, and mental health goals. Our experienced professionals will work with you to create a personalized treatment plan that meets your unique needs. Contact us now to start your journey towards lasting relief and improved well-being. Your path to a better life begins here.

    Ready to Book An Appointment With Our Psychiatrists?

    Our Latest Blogs

    Schedule your appointment:

    * Any patient needing a controlled substance needs a face-to-face appointment with the provider prior to the prescription being sent to be compliant with the DEA guidelines.

    • Step 1
      Select your desired appointment type.
    • Step 2
      Choose your staff member and desired location or leave as “ALL,” and we will match you!
    • Step 3
      Search for your date range and select from available times.

    We Look Forward to Seeing You!

    Policy, Procedures & Forms

    Click on the items below to download forms. 

    Release of Information Form

    Review Our Policies and Procedures

    Download Intake Forms

    Billing/Insurance Questions

    Contact Vanessa for any Billing and Insurance related questions. Find the contact information below. 

    Follow Us on Facebook!